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Drug ReportsGlutamic acid
D-glutamate
D-glutamate is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Drug Products
FDA
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name
Status
Last Update
aminosyn iiNew Drug Application2022-05-04
aminosyn-pfNew Drug Application2022-07-21
clinisolANDA2018-06-01
kabivenNew Drug Application2023-08-02
perikabivenNew Drug Application2023-08-07
plenamineANDA2023-04-21
premasol - sulfite-free (amino acid)ANDA2022-08-04
prosolNew Drug Application2020-10-07
trophamineNew Drug Application2023-11-27
Indications
FDA
EMA
No data
Agency Specific
FDA
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No data
Clinical
Clinical Trials
467 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
DepressionD003863—F33.91013451546
Depressive disorderD003866EFO_1002014F32.A711421842
Major depressive disorderD003865EFO_0003761F22711431439
Non-small-cell lung carcinomaD002289——920111137
SchizophreniaD012559EFO_0000692F205544523
AlcoholismD000437EFO_0003829F10.136—2415
Bipolar disorderD001714EFO_0000289F30.92412514
Obsessive-compulsive disorderD009771EFO_0004242F4229—1313
Parkinson diseaseD010300EFO_0002508G2027—1210
Psychotic disordersD011618—F20.8112—3410
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Lung neoplasmsD008175—C34.904167—327
Healthy volunteers/patients———1351—421
CarcinomaD002277—C80.0872——14
SyndromeD013577———32—712
Diabetes mellitusD003920EFO_0000400E08-E13272—312
Type 1 diabetes mellitusD003922EFO_0001359E10282—212
Treatment-resistant depressive disorderD061218——251—311
AdenocarcinomaD000230——461——10
Ovarian neoplasmsD010051EFO_0003893C56431——7
Brain injuriesD001930—S06.9151——7
Show 72 more
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Prostatic neoplasmsD011471—C61310——215
NeoplasmsD009369—C8076——112
Pancreatic neoplasmsD010190EFO_0003860C2578———9
Breast neoplasmsD001943EFO_0003869C5054——29
Compulsive personality disorderD003193—F60.526——28
StrokeD020521EFO_0000712I63.9—4——26
Autistic disorderD001321EFO_0003758F84.031——26
Triple negative breast neoplasmsD064726——34———5
MelanomaD008545——32———4
Autism spectrum disorderD000067877—F84.011——24
Show 104 more
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
ObesityD009765EFO_0001073E66.91———23
Human influenzaD007251EFO_0007328J11.13————3
Pulmonary hypertensionD006976EFO_0001361I27.201———12
Marijuana abuseD002189EFO_0007191F122————2
Hepatocellular carcinomaD006528—C22.01———12
Positron-emission tomographyD049268——1———12
PharmacokineticsD010599——2————2
Severe acute respiratory syndrome-related coronavirusD045473NCBITaxon_227859—2————2
Pervasive child development disordersD002659EFO_0003756F841———12
HyperkinesisD006948——1———12
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Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
BurnsD002056—T30.0————55
Problem behaviorD000066553——————22
Chronic obstructive pulmonary diseaseD029424EFO_0000341J44.9————22
Lung diseasesD008171EFO_0003818J98.4————22
Sars-cov-2D000086402——————22
Migraine disordersD008881EFO_0003821G43————22
Post-traumatic stress disordersD013313EFO_0001358F43.1————22
Traumatic stress disordersD040921——————22
Irritable bowel syndromeD043183EFO_0000555K58————22
Systemic lupus erythematosusD008180EFO_0002690M32————22
Show 79 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameD-glutamate
INN—
Description
D-glutamic acid is an optically active form of glutamic acid having D-configuration. It has a role as an Escherichia coli metabolite and a mouse metabolite. It is a D-alpha-amino acid and a glutamic acid. It is a conjugate acid of a D-glutamate(1-). It is an enantiomer of a L-glutamic acid.
Classification
Small molecule
Drug class—
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
N[C@H](CCC(=O)O)C(=O)O
Identifiers
PDB—
CAS-ID6893-26-1
RxCUI—
ChEMBL IDCHEMBL76232
ChEBI ID15966
PubChem CID23327
DrugBankDB02517
UNII ID—
Target
No data
Variants
No data
Financial
No data
Trends
No data
Safety
Black-box Warning
Black-box warning for: Aminosyn ii
Adverse Events
Top Adverse Reactions
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286 adverse events reported
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